Functional Deregulation of KIT

the effect of functional/notional approach on the proficiency level of efl learners and its evaluation through functional test

in fact, this study focused on the following questions: 1. is there any difference between the effect of functional/notional approach and the structural approaches to language teaching on the proficiency test of efl learners? 2. can a rather innovative language test referred to as "functional test" ge devised so so to measure the proficiency test of efl learners, and thus be as much reliable an...

Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool.

The stem cell factor (SCF)/Kit system has served as a classic model in deciphering molecular signaling events in the hematopoietic compartment, and Kit expression is a most critical marker for hematopoietic stem cells (HSCs) and progenitors. However, it remains to be elucidated how Kit expression is regulated in HSCs. Herein we report that a cytoplasmic tyrosine phosphatase Shp2, acting downstr...

Auburn: A Kit for Benchmarking Functional Data Structures

Benchmarking competing implementations of a data structure can be both tricky and time consuming. The eeciency of an implementation may depend critically on how it is used. This problem is compounded by persistence. All purely functional data structures are persistent. We present a kit that can generate benchmarks for a given data structure. A benchmark is made from a description of how it shou...

The Effects of Deregulation

Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation

Multidomain proteins incorporating interaction domains are central to regulation of cellular processes. The elucidation of structural organization and mechanistic insights into many of these proteins, however, remain challenging due to their inherent flexibility. Here, we describe the organization and function of four interaction domains in PLCγ1 using a combination of structural biology and bi...